Molecular determinants of phase separation for Drosophila DNA replication licensing factors
Parker MW, Kao JA, Huang AT, Berger JM, Botchan MR
A new class of disordered elements controls DNA replication through initiator self-assembly.
Parker MW, Bell M, Mir M, Kao JA, Darzacq X, Botchan MR, Berger JM
Design, synthesis, and evaluation of a novel benzamidine-based inhibitor of VEGF-C binding to Neuropilin-2.
Bioorganic Chemistry, 2020
Said AM, Parker MW, Vander Kooi CW
Mechanisms and regulation of DNA replication initiation in eukaryotes.
Critical Reviews in Biochemistry and Molecular Biology, 2017
Parker MW, Botchan MR, Berger JM
Plate-Based Assay for Measuring Direct Semaphorin-Neuropilin Interactions.
Methods in Molecular Biology, 2017
Parker MW, Vander Kooi CW
Expanding the 3-O-Sulfate Proteome--Enhanced Binding of Neuropilin-1 to 3-O-Sulfated Heparan Sulfate Modulates Its Activity.
ACS Chemical Biology, 2016
Thacker BE, Seamen E, Lawrence R, Parker MW, Xu Y, Liu J, Vander Kooi CW, Esko JD.
Structural basis for VEGF-C binding to neuropilin-2 and sequestration by a soluble splice form.
Parker MW, Linkugel AD, Goel HL, Wu T, Mercurio AM, Vander Kooi CW
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.
Molecular Cell, 2015
Raththagala M, Brewer MK, Parker MW, Sherwood AR, Wong BK, Hsu S, Bridges TM, Paasch BC, Hellman LM, Husodo S, Meekins DA, Taylor AO, Turner BD, Auger KD, Dukhande VV, Chakravarthy S, Sanz P, Woods VL Jr, Li S, Vander Kooi CW, Gentry MS.
Control of cellular motility by neuropilin-mediated physical interactions.
Biomolecular Concepts, 2014
Li X, Parker MW, Vander Kooi CW
Microplane-based screening for small molecule inhibitors of neuropilin-2/vascular endothelial growth factor-C interactions.
Analytical Biochemistry, 2014
Parker MW, Vander Kooi CW
Mechanistic basis for the potent anti-angiogenic activity of semaphorin 3F.
Guo HF, Li X, Parker MW, Waltenberger J, Becker PM, Vander Kooi CW
Effect of C-terminal sequence on competitive semaphorin binding to neuropilin-1
The Journal of Molecular Biology, 2013
Parker MW, Linkugel AD, Vander Kooi CW
Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition.
PLoS One, 2012
Parker MW, Xu P, Guo HF, Vander Kooi CW
Function of members of the neuropilin family as essential pleiotropic cell surface receptors.
Parker MW, Guo HF, Li X, Linkugel AD, Vander Kooi CW
Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1.
The Journal of Biological Chemistry, 2012
Parker MW, Xu P, Li X, Vander Kooi CW
Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin.
Parker MW, Hellman LM, Xu P, Fried MG, Vander Kooi CW